I'm a stickler for maintenance and tend to keep things for a long time.
On every motor I own, at every oil change, I use some sort of fuel system cleaner.
I like Techron Fuel system Cleaner, Lucas (upper cyl lube/inj cleaner), or Sea Foam. Those are my top three. Whichever is on sale. One of them usually is. And also provides for a variety of each products special forte'.
On my cars, trucks, etc I just use regular unleaded (with up to10% ethanol). But on the bikes, mowers, etc. I always prefer the non-eth fuels. Not always possible, but mostly is.
Anyway, I've never had carb/inj tuning issues.
It's a simple and relatively cheap way to keep things tidy inside your internal combustion engines.
Thanks for the research!